https://ods.od.nih.gov/factsheets/Carnitine-HealthProfessional/

• synthesized endogenously in the liver, kidneys, and brain from the amino acids lysine and methionine
• an essential cofactor that helps transport long-chain fatty acids into the mitochondria
• also helps transport some toxic compounds out of the mitochondria
• a strict vegetarian diet, for example, synthesizes approximately 14.4 mg/day carnitine - dietary requirement 15mg/d
• The study found that L-carnitine significantly reduced rates of all-cause mortality, ventricular arrhythmias, and new-onset angina but did not affect risk of heart failure or myocardial reinfarction

• Pomegranate contains substantial amount of ellagitannins (a type of polyphenol)
• polyphenols thought to have role in ACE inhibition as well as increasing NO levels

• contains monacolin K - has the same chemical structure as lovastatin
• same action with same side effects
• blocks liver HMG-CoA reductase to reduce cholesterol production
• myopathy, hepatotoxicity, and diabetes mellitus being the most common adverse reactions
• different statins metabolised differently - statin review
  • Fluvastatin, lovastatin, pravastatin, and simvastatin have a relatively short half-life.
  • atorvastatin and rosuvastatin have longer half-lives
  • HMG-CoA reductase inhibitors are excreted into bile and faeces

• Digestive issues: Bloating, gas, heartburn, nausea, and stomach pain.
• Headaches and dizziness: Mild neurological symptoms are frequently reported.
• Muscle aches: Mild soreness and fatigue in muscles are common.

https://www.mdpi.com/1422-0067/21/18/6695